The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2025

Filed:

Nov. 07, 2022
Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Kathryn L. Aron, Acton, MA (US);

Jeffrey Swanberg, Maynard, MA (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/36 (2006.01); C12M 1/34 (2006.01);
U.S. Cl.
CPC ...
C12M 41/48 (2013.01); C12M 41/12 (2013.01); C12M 41/46 (2013.01);
Abstract

The present invention relates to the use of online biomass capacitance monitoring in cultures as a way to control the growth of cells through the use of a temperature control loop. In certain embodiments, a biomass capacitance probe is used to measure the cell density, and a predetermined growth curve is used to adjust the temperature in the culture.


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