The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2025

Filed:

Jun. 18, 2024
Applicant:

Corning Incorporated, Corning, NY (US);

Inventors:

Ann Meejin Ferrie, Salem, NH (US);

Vasiliy Nikolaevich Goral, Painted Post, NY (US);

Lori Eileen Romeo, Elmira Heights, NY (US);

Assignee:

CORNING INCORPORATED, Corning, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/12 (2006.01); C12M 1/00 (2006.01); C12M 1/34 (2006.01); C12M 3/00 (2006.01); C12N 5/00 (2006.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
C12M 25/14 (2013.01); C12M 23/02 (2013.01); C12M 23/20 (2013.01); C12M 23/44 (2013.01); C12M 25/04 (2013.01); C12M 29/10 (2013.01); C12M 29/26 (2013.01); C12M 41/26 (2013.01); C12M 25/02 (2013.01); C12N 5/0068 (2013.01); C12N 5/0602 (2013.01); C12N 2513/00 (2013.01); C12N 2533/30 (2013.01); C12N 2533/40 (2013.01); C12N 2533/90 (2013.01); C12N 2535/00 (2013.01);
Abstract

A cell culture matrix is provided that has a substrate with a first side, a second side opposite the first side, a thickness separating the first side and the second side, and a plurality of openings formed in the substrate and passing through the thickness of the substrate. The plurality of openings allow flow of at least one of cell culture media, cells, or cell products through the thickness of the substrate, and provides a uniform, efficient, and scalable matrix for cell seeding, proliferation, and culturing. The substrate can be formed from a woven polymer mesh material that provides a high surface area to volume ratio for cells and good fluid flow through the matrix. Bioreactor systems incorporating the cell culture matrix and related methods are also provided.


Find Patent Forward Citations

Loading…