The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2025

Filed:

Nov. 14, 2018
Applicant:

The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);

Inventors:

Mark H. Schoenfisch, Chapel Hill, NC (US);

Lei Yang, Carrboro, NC (US);

Haibao Jin, Carrboro, NC (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08G 73/02 (2006.01); A61K 31/785 (2006.01); A61L 2/16 (2006.01); C08G 83/00 (2006.01);
U.S. Cl.
CPC ...
C08G 73/028 (2013.01); A61K 31/785 (2013.01); A61L 2/16 (2013.01); C08G 83/006 (2013.01); A61L 2202/24 (2013.01);
Abstract

Several embodiments of hyperbranched structures are disclosed. In some embodiments, the hyperbranched structures are covalently modified to store and release nitric oxide. Some embodiments pertain to methods of making and also to the use of hyperbranched structures. The covalently modified hyperbranched structures may be tailored to release nitric oxide in a controlled manner and are useful for eradication of both gram positive and gram negative bacteria as well as other microbes.


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