The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2025
Filed:
Jul. 08, 2020
California Institute of Technology, Pasadena, CA (US);
The Rockefeller University, New York, NY (US);
Stuart A. Sievers, Encino, CA (US);
Jennifer Keeffe, Pasadena, CA (US);
Michel C. Nussenzweig, New York, NY (US);
Pamela J. Bjorkman, La Canada, CA (US);
California Institute of Technology, Pasadena, CA (US);
The Rockefeller University, New York, NY (US);
Abstract
This disclosure provides novel broadly neutralizing anti-HIV antibodies and antigen-binding fragments thereof. The disclosed anti-HIV antibodies exhibited improved biophysical properties, e.g., reduced polyreactivity, prolonged half-life, while retaining broad and potent neutralization activity. The anti-HIV bNAb variants as disclosed constitute a novel therapeutic strategy for treating and/or preventing HIV infection.