The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2025

Filed:

Nov. 19, 2019
Applicant:

Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);

Inventors:

Dan H. Barouch, Newton, MA (US);

Bruce A. Kerwin, Bainbridge Island, WA (US);

Randal R. Ketchem, Snohomish, WA (US);

Alison J. Gillespie, Seattle, WA (US);

Christine C. Siska, Seattle, WA (US);

Rutilio H. Clark, Bainbridge Island, WA (US);

Julee A. Floyd, Seattle, WA (US);

Jeremy M. Shaver, Lake Forest Park, WA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 45/06 (2006.01); C07K 16/10 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1045 (2013.01); A61K 45/06 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01);
Abstract

Featured are PGDM1400 variant antibodies or fragments thereof, which can be administered, e.g., as antibody therapies for treating human immunodeficiency virus (HIV) infection. In particular, featured are methods of treating or curing subjects infected with HIV and/or preventing HIV infections in subjects at risk of HIV transmission using the PGDM1400 variant antibodies or fragments thereof.


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