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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12459988 B1

PDFFull Text
Date of Patent:
Nov. 04, 2025

Filed:

Oct. 11, 2024

Chimeric protein comprising an anti-influenza virus antibody moiety and a mucoadhesive peptide fragment for preventing or treating influenza infections

Applicant:

Invisishield Technologies Ltd., Emeryville, CA (US);

Inventors:

Cheng Liu, Orinda, CA (US);

Ziyou Cui, Seattle, WA (US);

Hongbing Zhang, Moraga, CA (US);

Zhiyuan Yang, Richmond, CA (US);

Guangyan Xiong, Emeryville, CA (US);

Lu Jin, Emeryville, CA (US);

Jinyun Chen, Emeryville, CA (US);

Motao Liu, Emeryville, CA (US);

Warner Greene, Hillsborough, CA (US);

Assignee:

INVISISHIELD TECHNOLOGIES LTD., Emeryville, CA (US);

Attorney:

MORRISON & FOERSTER LLP

Primary Examiner:

Zachary C Howard

Int. Cl.
CPC ...
C07K 7/06 (2006.01); A61K 38/08 (2019.01); A61K 38/10 (2006.01); A61K 39/42 (2006.01); A61K 39/44 (2006.01); A61K 47/64 (2017.01); A61P 31/16 (2006.01); C07K 7/08 (2006.01); C07K 16/10 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1018 (2013.01); A61K 38/08 (2013.01); A61K 38/10 (2013.01); A61K 39/42 (2013.01); A61K 39/44 (2013.01); A61K 47/645 (2017.08); A61P 31/16 (2018.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); A61K 2039/505 (2013.01); C07K 2317/565 (2013.01); C07K 2319/00 (2013.01);
Abstract

The present application provides chimeric proteins comprising an antibody moiety that specifically binds to a component of an influenza virus or a variant thereof, and a positively charged mucoadhesive peptide fragment. Compositions comprising the chimeric proteins described herein are useful for preventing or treating an infection caused by an influenza virus or a variant thereof in an individual.

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