The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2025

Filed:

Mar. 02, 2021
Applicant:

Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd., Zhejiang, CN;

Inventors:

Haiwen Hu, Zhejiang, CN;

Li Fang, Zhejiang, CN;

Fan Hu, Zhejiang, CN;

Fenfen Chen, Zhejiang, CN;

Xinjie Zhou, Zhejiang, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/056 (2006.01);
U.S. Cl.
CPC ...
C07D 491/056 (2013.01); C07B 2200/13 (2013.01);
Abstract

The invention relates to a crystal form A of (S)-2-(3S,8S)-3-(4-(3,4-dichlorobenzyloxy)phenyl-7-((S)-1-phenylpropyl)-2,3,6,7,8,9-hexahydro-[1,4]-dioxino[2,3-g]isoquinolin-8-ylformylamino)-3-(4-(2,3-dimethylpyridin-4-yl)phenyl)propionic acid ('OAD2'), and methods of preparation thereof. Crystal form A may be useful in the treatment of various conditions and metabolic disorders including, but not limited to, type 2 diabetes.


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