The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2025
Filed:
Aug. 27, 2021
Applicant:
Madera Therapeutics, Llc, Cary, NC (US);
Inventor:
Edwin Iwanowicz, Cary, NC (US);
Assignee:
Madera Therapeutics, LLC, Cary, NC (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/14 (2006.01); A61P 35/00 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/14 (2013.01); A61P 35/00 (2018.01); C07D 471/04 (2013.01);
Abstract
Use of caseinolytic protease P (ClpP) function and/or concentration as a biomarker for predicting the response of a neoplastic disease, preferably cancer or another disease where enhancing ClpP activity may provide a therapeutic benefit, to a compound of Formula I. In other aspects it relates to methods and kits, as well as methods of treatment involving the use of the biomarker.
Iwanowicz, Edwin. (2025). Use of caseinolytic protease p function as a biomarker of drug response to imipridone-like agents (U.S. Patent No. 12459945). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12459945
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile