The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2025
Filed:
May. 07, 2024
Applicant:
Nodthera Limited, Little Chesterford, GB;
Inventors:
Assignee:
NodThera Limited, Little Chesterford, GB;
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01); C07D 231/38 (2006.01); C07D 237/20 (2006.01); C07D 239/42 (2006.01); C07D 249/04 (2006.01); C07D 249/14 (2006.01); C07D 261/14 (2006.01); C07D 277/52 (2006.01); C07D 285/135 (2006.01); C07D 307/66 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01); C07D 471/08 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); C07D 231/38 (2013.01); C07D 237/20 (2013.01); C07D 239/42 (2013.01); C07D 249/04 (2013.01); C07D 249/14 (2013.01); C07D 261/14 (2013.01); C07D 277/52 (2013.01); C07D 285/135 (2013.01); C07D 307/66 (2013.01); C07D 401/12 (2013.01); C07D 405/12 (2013.01); C07D 471/08 (2013.01); C07B 2200/05 (2013.01);
Abstract
The present disclosure relates to compounds of Formula (I): and to their pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein are useful for inhibiting the maturation of cytokines of the IL-1 family by inhibiting inflammasomes and may be used in the treatment of disorders in which inflammasome activity is implicated, such as inflammatory, autoinflammatory and autoimmune diseases and cancers.