The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2025
Filed:
Jun. 22, 2020
Applicant:
Guangzhou Ocusun Ophthalmic Biotechnology Co., Ltd., Guangzhou, CN;
Inventors:
Yizhi Liu, Guangzhou, CN;
Yandong Wang, Guangzhou, CN;
Lingyun Wu, Guangzhou, CN;
Xu You, Guangzhou, CN;
Zheming Xiao, Guangzhou, CN;
Shuhui Chen, Guangzhou, CN;
Assignee:
GUANGZHOU OCUSUN OPTHALMIC BIOTECHNOLOGY CO., LTD., Guangzhou, CN;
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); A61P 27/06 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); A61P 27/06 (2018.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01);
Abstract
Disclosed are a series of isoquinolone derivatives as ROCK protein kinase inhibitors and uses thereof in preparing medicaments for ROCK protein kinase inhibitor-related glaucoma or ocular hypertension diseases. Specially, disclosed are a compound of formula (I), an isomer thereof or a pharmaceutically acceptable salt thereof.