The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2025

Filed:

Jul. 09, 2020
Applicant:

The George Washington University, WasHington, DC (US);

Inventors:

Michael Keidar, Baltimore, MD (US);

Dayun Yan, Ashburn, VA (US);

Xiaoliang Yao, Fairfax, VA (US);

Li Lin, Arlington, VA (US);

Vikas Soni, Washington, DC (US);

Jonathan Sherman, Potomac, MD (US);

Assignee:

THE GEORGE WASHINGTON UNIVERSITY, Washington, DC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 2/00 (2006.01); A61K 31/495 (2006.01); A61N 5/10 (2006.01); A61P 35/00 (2006.01); A61B 18/00 (2006.01);
U.S. Cl.
CPC ...
A61N 2/004 (2013.01); A61K 31/495 (2013.01); A61P 35/00 (2018.01); A61B 2018/00071 (2013.01); A61B 2018/00583 (2013.01); A61N 5/10 (2013.01);
Abstract

A method and system of sensitization of cancerous cells in a volume is disclosed. A plasma tube including a pair of electrodes coupled to a power supply is provided. The plasma tube generates a plasma jet between the electrodes. A controller is coupled to a power supply to control a discharge voltage to the electrodes to generate the plasma jet and direct an electro-magnetic field at the volume having cancerous cells and normal cells for a sufficient time to sensitize the cancer cells. A treatment device applies a treatment such as TMZ to the sensitized cancer cells after the cancer cells are sensitized by the electro-magnetic field.


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