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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12458731 B1

PDFFull Text
Date of Patent:
Nov. 04, 2025

Filed:

Aug. 17, 2016

Mesenchymal cell-binding composite material for tissue restoration

Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventors:

Russell Martin, Baltimore, MD (US);

Hai-Quan Mao, Baltimore, MD (US);

Sashank Reddy, Baltimore, MD (US);

Justin Sacks, Baltimore, MD (US);

Xiaowei Li, Towson, MD (US);

Brian Honewee Cho, Baltimore, MD (US);

Assignee:

The Johns Hopkins University, Baltimore, MD (US);

Attorney:

Fox Rothschild LLP

Primary Examiner:

Catherine S Hibbert

Int. Cl.
CPC ...
A61L 27/52 (2006.01); A61K 35/28 (2015.01); A61K 38/08 (2019.01); A61K 39/395 (2006.01); A61L 27/36 (2006.01); A61L 27/38 (2006.01); A61L 27/48 (2006.01); A61L 27/54 (2006.01); A61L 27/56 (2006.01); A61L 27/58 (2006.01); A61L 27/60 (2006.01); C12N 5/0775 (2010.01);
U.S. Cl.
CPC ...
A61L 27/48 (2013.01); A61K 35/28 (2013.01); A61K 38/08 (2013.01); A61K 39/395 (2013.01); A61L 27/3604 (2013.01); A61L 27/3608 (2013.01); A61L 27/38 (2013.01); A61L 27/3834 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); A61L 27/58 (2013.01); A61L 27/60 (2013.01); C12N 5/0667 (2013.01); A61L 2400/06 (2013.01); A61L 2430/34 (2013.01); C12N 2513/00 (2013.01); C12N 2533/30 (2013.01); C12N 2533/90 (2013.01);
Abstract

The presently disclosed composition and methods are provided for a nanofiber-hydrogel composite containing adipose cell binding moieties. A method for healing a soft tissue defect can include applying an adipose cell-binding composite material to a soft tissue defect in combination with exogenous adipose-derived cells or endogenous cells recruited from the surrounding tissue.

Find Patent Forward Citations

Martin, Russell. (2025). Mesenchymal cell-binding composite material for tissue restoration (U.S. Patent No. 12458731). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12458731

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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