The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2025

Filed:

Nov. 13, 2019
Applicant:

Korea Institute of Science and Technology, Seoul, KR;

Inventors:

Jeongjin Kim, Seoul, KR;

Hea-Jin Kim, Seoul, KR;

Yuliia Steshenko, Seoul, KR;

Sejin Jeon, Seoul, KR;

Hyunsoo Park, Seoul, KR;

Wooyeon Shin, Seoul, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); A01K 67/0278 (2024.01); A61K 41/00 (2020.01); A61K 48/00 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/164 (2013.01); A01K 67/0278 (2013.01); A61K 41/00 (2013.01); A61P 25/00 (2018.01); A01K 2227/105 (2013.01); A01K 2267/03 (2013.01); A61K 48/00 (2013.01);
Abstract

The present invention relates to a method for treating autism spectrum disorder, a mouse for monitoring autism spectrum disorder, and a method for screening a candidate for preventing or treating autism spectrum disorder. Specifically, according to the present invention, the output signal (or excitation of population) of neurons of the ventrolateral thalamus (VL), the laterodorsal thalamus (LD) or the striatum may be suppressed by introducing a halorhodopsin protein into neurons of the ventrolateral thalamus (VL), the laterodorsal thalamus (LD) or the striatum and then irradiating light to induce hyperpolarization of the halorhodopsin protein. Thus, the present invention has the effect of preventing or treating autism.


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