The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2025

Filed:

Jun. 30, 2023
Applicant:

The General Hospital Corporation, Boston, MA (US);

Inventors:

Dilip Paithankar, Wayland, MA (US);

Richard Dean Blomgren, Dacula, GA (US);

Richard Rox Anderson, Boston, MA (US);

William A. Farinelli, Danvers, MA (US);

Apostolos G. Doukas, Cambridge, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 33/242 (2019.01); A61K 9/00 (2006.01); A61K 9/50 (2006.01); A61K 9/51 (2006.01); A61K 33/24 (2019.01); A61K 33/243 (2019.01); A61K 41/00 (2020.01);
U.S. Cl.
CPC ...
A61K 33/242 (2019.01); A61K 9/0009 (2013.01); A61K 9/0014 (2013.01); A61K 9/50 (2013.01); A61K 9/5115 (2013.01); A61K 33/24 (2013.01); A61K 33/243 (2019.01); A61K 41/0047 (2013.01);
Abstract

The present invention provides compositions comprising energy (e.g., light) absorbing submicron particles (e.g., nanoparticles comprising a silica core and a gold shell) and methods for delivering such particles via topical application. This delivery is facilitated by application of mechanical agitation (e.g. massage), acoustic vibration in the range of 10 Hz-20 kHz, ultrasound, alternating suction and pressure, and microjets.


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