The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2025
Filed:
Jun. 17, 2021
Applicant:
Ji Xing Pharmaceuticals Hong Kong Limited, Causeway Bay, HK;
Inventors:
Steven Sparks, Apex, NC (US);
Christopher M. Yates, Raleigh, NC (US);
Sammy R. Shaver, Chapel Hill, NC (US);
William J. Hoekstra, Durham, NC (US);
Assignee:
Corxel Pharmaceuticals Hong Kong Limited, Causeway Bay, HK;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/501 (2006.01); A61K 31/4184 (2006.01); A61K 31/4188 (2006.01); A61K 31/437 (2006.01); A61P 1/00 (2006.01); A61P 3/00 (2006.01); A61P 9/00 (2006.01); A61P 35/00 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 403/14 (2006.01); C07D 405/14 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/501 (2013.01); A61K 31/4184 (2013.01); A61K 31/4188 (2013.01); A61K 31/437 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01);
Abstract
Provided are compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders, or symptoms thereof mediated by such metalloenzymes. In some embodiments, a provided compound is a compound of Formula I, or a pharmaceutically acceptable salt thereof. In some embodiments, a provided method is a method of alleviating or abating a disorder or disease associated with aldosterone synthase (CYP11B2) or ameliorating a symptom thereof.