The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2025
Filed:
Aug. 20, 2020
Applicants:
Otsuka Pharmaceutical Co., Ltd., Tokyo, JP;
Taiho Pharmaceutical Co., Ltd., Tokyo, JP;
Inventors:
Steven Howard, Cambridge, GB;
John Walter Liebeschuetz, Cambridge, GB;
Tadashi Shimamura, Tsukuba, JP;
Assignees:
OTSUKA PHARMACEUTICAL CO., LTD., Tokyo, JP;
TAIHO PHARMACEUTICAL CO., LTD., Tokyo, JP;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4985 (2006.01); A61K 9/00 (2006.01); A61K 9/19 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01); A61K 45/06 (2006.01); A61K 47/10 (2017.01); A61K 47/26 (2006.01); A61P 35/00 (2006.01); C07D 487/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4985 (2013.01); A61K 9/0019 (2013.01); A61K 9/19 (2013.01); A61K 9/2013 (2013.01); A61K 9/2018 (2013.01); A61K 9/4825 (2013.01); A61K 45/06 (2013.01); A61K 47/10 (2013.01); A61K 47/26 (2013.01); A61P 35/00 (2018.01); C07D 487/04 (2013.01); C07D 519/00 (2013.01);
Abstract
The invention provides new pyrazine derivatives of formula (I): or a tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the substituents are as defined herein. The invention also provides pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.