The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2025
Filed:
Jan. 13, 2021
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Michael Karin, La Jolla, CA (US);
Hua Su, La Jolla, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/427 (2006.01); A61K 31/137 (2006.01); A61K 31/366 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/427 (2013.01); A61K 31/137 (2013.01); A61K 31/366 (2013.01); A61P 35/00 (2018.01);
Abstract
Provided herein are methods and compositions for treating cancer through a combination of an inhibitor of macropinocytosis upregulation and an autophagy inhibitor. Also provided are methods and compositions for inducing cell death of cancer cells, and transgenic animal models regarding same.