The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2025

Filed:

Dec. 01, 2020
Applicant:

Daljit Singh Dhanoa, Del Mar, CA (US);

Inventor:

Daljit Singh Dhanoa, Del Mar, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 45/06 (2006.01); A61K 31/36 (2006.01); A61K 31/4184 (2006.01); A61K 31/519 (2006.01); A61P 13/08 (2006.01); A61P 35/00 (2006.01); C07D 317/60 (2006.01);
U.S. Cl.
CPC ...
A61K 31/36 (2013.01); A61K 31/4184 (2013.01); A61K 31/519 (2013.01); A61P 13/08 (2018.01); C07D 317/60 (2013.01); C07B 2200/05 (2013.01);
Abstract

The present invention is concerned with deuterium-enriched substituted phenoxy-(3, 4-methylenedioxy)phenylacetic acid and acylsulfonamide derivatives of general structural formula I, their optically active or pure enantiomers and diastereomers, and pharmaceutical salts thereof, These compounds have selective antagonist activity for endothelin receptors or both endothelin and angiotensin II receptors, and are useful in the treatment of diseases mediated by endothelin and angiotensin-II and their receptors.


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