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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12458600 B1

PDFFull Text
Date of Patent:
Nov. 04, 2025

Filed:

Feb. 08, 2021

Method for producing granules containing a core particle, granules containing a core particle, pharmaceutical composition containing the granules containing the core particle, and preparation containing the pharmaceutical composition

Applicant:

Sawai Pharmaceutical Co., Ltd., Osaka, JP;

Inventors:

Wataru Izui, Osaka, JP;

Kenji Nozawa, Osaka, JP;

Hiroyuki Yamamoto, Osaka, JP;

Ryota Kimata, Osaka, JP;

Naoki Yoshihara, Osaka, JP;

Assignee:

SAWAI PHARMACEUTICAL Co., Ltd., Osaka, JP;

Attorney:

HAUPTMAN HAM, LLP

Primary Examiner:

Lakshmi S Channavajjala

Int. Cl.
CPC ...
A61K 9/16 (2006.01); A61K 31/13 (2006.01); A61K 31/137 (2006.01); A61K 31/343 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1694 (2013.01); A61K 9/1623 (2013.01); A61K 9/1635 (2013.01); A61K 9/1652 (2013.01); A61K 9/167 (2013.01); A61K 31/13 (2013.01); A61K 31/137 (2013.01); A61K 31/343 (2013.01);
Abstract

A method for producing granules containing a core particle by using a general granulation method is provided. Granules containing a core particle produced by the method are provided. In addition, a pharmaceutical composition and preparation containing the granules containing the core particle are provided. The granulation method according to an embodiment of the present invention granulates by spraying granulation liquid having a mist diameter (D) not more than the particle size (D) of the core particle on a mixture containing a drug substance and a core particle. The granulation liquid may be water. The particle size of the core particle (D) may be larger than the particle size (D) of the drug substance.

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Izui, Wataru. (2025). Method for producing granules containing a core particle, granules containing a core particle, pharmaceutical composition containing the granules containing the core particle, and preparation containing the pharmaceutical composition (U.S. Patent No. 12458600). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12458600

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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