The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 2025
Filed:
May. 17, 2022
Applicant:
Autolus Limited, London, GB;
Inventors:
Martin Pulé, London, GB;
Shaun Cordoba, London, GB;
Simon Thomas, London, GB;
Shimobi Onuoha, London, GB;
Mathieu Ferrari, London, GB;
Wen Chean Lim, London, GB;
Biao Ma, London, GB;
Assignee:
AUTOLUS LIMITED, London, GB;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/42 (2025.01); A61P 35/00 (2006.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
C07K 16/2878 (2013.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/4211 (2025.01); A61K 40/4215 (2025.01); A61P 35/00 (2018.01); C07K 16/2803 (2013.01); C12N 5/0636 (2013.01); A61K 2239/28 (2023.05); C07K 2317/31 (2013.01); C07K 2317/55 (2013.01); C07K 2319/03 (2013.01);
Abstract
The present invention provides a chimeric antigen receptor (CAR) which binds a low density target antigen, which comprises a Fab antigen binding domain. The invention also relates to cells expressing such a CAR and their use in the treatment of disease.