The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 28, 2025

Filed:

Jul. 15, 2021
Applicant:

Chiesi Farmaceutici S.p.a., Parma, IT;

Inventors:

Elisabetta Armani, Parma, IT;

Gabriele Amari, Parma, IT;

Andrea Rizzi, Parma, IT;

Mafalda Pagano, Parma, IT;

Luca Raveglia, Parma, IT;

Claudia Beato, Parma, IT;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/04 (2006.01); C07D 231/40 (2006.01); C07D 249/06 (2006.01); C07D 333/36 (2006.01); C07D 401/04 (2006.01); C07D 409/04 (2006.01); C07D 413/14 (2006.01); C07D 417/04 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
C07D 413/04 (2013.01); C07D 231/40 (2013.01); C07D 249/06 (2013.01); C07D 333/36 (2013.01); C07D 401/04 (2013.01); C07D 409/04 (2013.01); C07D 413/14 (2013.01); C07D 417/04 (2013.01); C07D 417/14 (2013.01);
Abstract

The present invention relates to compounds of general formula (I) inhibiting lysophosphatidic acid receptor 1 (LPA1), particularly the invention relates to compounds that are Ami do cyclohexane acid derivatives, methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful in the treatment of diseases or conditions associated with a dysregulation of LPA receptors, in particular fibrosis.


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