The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 28, 2025

Filed:

Dec. 11, 2020
Applicant:

Grand Theravac Life Sciences (Nanjing) Co., Ltd., Nanjing, CN;

Inventors:

Jun Ge, Nanjing, CN;

Jianqiang Li, Nanjing, CN;

Jiaojiao Sun, Nanjing, CN;

Sulin Ren, Nanjing, CN;

Tong Zhou, Nanjing, CN;

Shiwei Wang, Nanjing, CN;

Xiaodong Wang, Nanjing, CN;

Jingfeng Huang, Nanjing, CN;

Yue Chen, Nanjing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 31/711 (2006.01); A61K 39/12 (2006.01); A61K 39/245 (2006.01); A61K 39/29 (2006.01); A61K 39/39 (2006.01); A61P 31/04 (2006.01); A61P 31/12 (2006.01); A61P 31/22 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39 (2013.01); A61K 31/711 (2013.01); A61K 39/245 (2013.01); A61K 39/29 (2013.01); A61K 39/292 (2013.01); A61P 31/04 (2018.01); A61P 31/12 (2018.01); A61P 31/22 (2018.01); C07K 16/2803 (2013.01); A61K 2039/55561 (2013.01); A61K 2039/55577 (2013.01);
Abstract

A pharmaceutical composition comprising: i) a herpes gE protein, an active fragment of the protein, a variant of the protein, or a mixture of at least two of them; ii) an immunostimulatory composition comprising a saponin and a CpG oligodeoxynucleotide, or consisting of an adjuvant comprising a saponin and a CpG oligodeoxynucleotide. Use of the pharmaceutical composition in the preparation of a medicament for preventing and/or treating a varicella-zoster virus infection and/or a varicella-zoster virus mediated disease. The pharmaceutical composition achieves an unexpected technical effect and can mediate a stronger immune response.


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