The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 28, 2025

Filed:

Aug. 17, 2022
Applicants:

The United States of America, As Represented BY the Secretary of Agriculture, Washington, DC (US);

Triad National Security, Llc, Los Alamos, NM (US);

Kansas State University Research Foundation, Manhattan, KS (US);

Inventors:

Aida E. Rieder, Westbrook, CT (US);

Katherine M. Pflaum, Middletown, CT (US);

Fayna C. Diaz San Segundo, Blue Point, NY (US);

William M. Fischer, Los Alamos, NM (US);

Tatjana Sitt, Essex, CT (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/135 (2006.01); A61P 31/14 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/135 (2013.01); A61P 31/14 (2018.01); A61K 2039/552 (2013.01);
Abstract

Synthetic foot-and-mouth disease virus (FMDV) mosaic polypeptides, and nucleic acid molecules encoding the mosaic polypeptides, are described. When included as part of an FMDV genome, the mosaic polypeptides permit virus replication and assembly into FMDV particles. The mosaic polypeptide and nucleic acid compositions can be used to elicit immune responses that provide protection against a broad range of serotype O FMDV strains.


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