The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 28, 2025

Filed:

Jun. 09, 2023
Applicant:

University of Miami, Miami, FL (US);

Inventors:

Evangelos V. Badiavas, Coral Gables, FL (US);

Arsalan Q. Shabbir, Miami, FL (US);

Stephen C. Davis, El Portal, FL (US);

Assignee:

UNIVERSITY OF MIAMI, Miami, FL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/28 (2015.01); A61K 8/98 (2006.01); A61K 35/12 (2015.01); A61K 35/16 (2015.01); A61K 35/22 (2015.01); A61Q 19/00 (2006.01); A61Q 19/08 (2006.01);
U.S. Cl.
CPC ...
A61K 35/28 (2013.01); A61K 8/981 (2013.01); A61K 8/983 (2013.01); A61K 35/12 (2013.01); A61K 35/16 (2013.01); A61K 35/22 (2013.01); A61Q 19/00 (2013.01); A61Q 19/08 (2013.01); A61K 2800/74 (2013.01); A61K 2800/86 (2013.01);
Abstract

The present invention relates to the fields of medicine, cell biology, molecular biology and genetics. In particular, the present invention provides methods to isolate and purify microvesicles from cell culture supernatants and biological fluids. The present invention also provides pharmaceutical compositions of microvesicles to promote or enhance wound healing, stimulate tissue regeneration, remodel scarred tissue, modulate immune reactions, alter neoplastic cell growth and/or mobility, or alter normal cell growth and/or mobility. The present invention also provides compositions of microvesicles to be used as diagnostic reagents, and methods to prepare the compositions of microvesicles.


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