The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 2025
Filed:
Dec. 11, 2020
Applicant:
University of South Florida, Tampa, FL (US);
Inventors:
Eleni Markoutsa, Tampa, FL (US);
Shyam S. Mohapatra, Lutz, FL (US);
Subhra Mohapatra, Lutz, FL (US);
Assignee:
University of South Florida, Tampa, FL (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/28 (2015.01); A61K 31/203 (2006.01); A61K 31/7088 (2006.01); C12N 5/0775 (2010.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 35/28 (2013.01); A61K 31/203 (2013.01); A61K 31/7088 (2013.01); C12N 5/0662 (2013.01); C12N 15/113 (2013.01); C12N 2310/113 (2013.01); C12N 2502/086 (2013.01);
Abstract
The present disclosure relates to exosomes isolated from mesenchymal stem cells exposed to a conditioned media in which microglial cells are cultured in the presence of lipopolysaccharide (LPS) or a beta-amyloid oligomer and uses thereof for reducing inflammation and for treating Alzheimer's disease.