The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 2025
Filed:
Nov. 29, 2024
Applicant:
The Second Affiliated Hospital of Soochow University, Suzhou, CN;
Inventors:
Assignee:
THE SECOND AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY, Suzhou, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4406 (2006.01); A61P 13/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4406 (2013.01); A61P 13/12 (2018.01);
Abstract
The present disclosure relates to the technical field of use of chidamide in drug preparation, particularly to use of chidamide in preparing a drug for treating renal fibrosis. The present disclosure proves that the chidamide can significantly improve the fibrosis of TGF-β stimulated HK2 cells. The chidamide significantly improves the renal fibrosis of UUO mice and ameliorates the renal fibrosis through a PI3K/Akt signaling pathway, so that the present disclosure has wide clinical application prospects.