The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2025

Filed:

Sep. 01, 2020
Applicant:

Sartorius Bioanalytical Instruments, Inc., Bohemia, NY (US);

Inventors:

Zhaoping Liu, Ann Arbor, MI (US);

Stephen Barnes, Ann Arbor, MI (US);

Dominique Perez, Ann Arbor, MI (US);

Christopher Suski, Ann Arbor, MI (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 35/00 (2006.01); G01N 33/50 (2006.01); G01N 35/10 (2006.01);
U.S. Cl.
CPC ...
G01N 35/0098 (2013.01); G01N 33/5002 (2013.01); G01N 35/0099 (2013.01); G01N 35/10 (2013.01); G01N 2035/00524 (2013.01); G01N 2035/00564 (2013.01); G01N 2035/1053 (2013.01);
Abstract

The present disclosure provides a method for automatic sampling of immune cells from a biological fluid sample, e.g., whole blood, deposited in a well of a microwell plate. The microwell plate is placed on a shaker having a magnetic adapter including at least one magnet. The magnet causes red blood cells (RBCs) bound to magnetic beads to be attracted to and migrate to a wall of the well. The shaker is then operated to shake the microwell plate such that the immune cells are substantially isolated from the RBCs in a region of the well. A sample probe is then lowered into the region of the well to withdraw a portion of the sample containing the immune cells.


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