The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2025

Filed:

Aug. 30, 2024
Applicant:

Lumiere Therapeutics Co., Ltd., Jiangsu, CN;

Inventors:

Bohong Chen, Guangzhou, CN;

Yang Hu, Guangzhou, CN;

Yulin Yu, Guangzhou, CN;

Wenqiong Tan, Guangzhou, CN;

Shaoyun Lin, Guangzhou, CN;

Wenchang Xu, Guangzhou, CN;

Youyu Wu, Guangzhou, CN;

Xiaojie Ma, Guangzhou, CN;

Jiajun Yu, Guangzhou, CN;

Jinshuai Sun, Guangzhou, CN;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); C12N 9/78 (2006.01); C12N 15/11 (2006.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
C12N 15/90 (2013.01); C12N 9/22 (2013.01); C12N 9/78 (2013.01); C12N 15/11 (2013.01); C12Y 305/04004 (2013.01); C12N 2310/20 (2017.05); C12N 2310/531 (2013.01);
Abstract

Disclosed herein are a Cas12i polypeptide and use thereof in a CRISPR-Cas system. Specifically disclosed herein are a Cas12i polypeptide, a Cas12i fusion polypeptide, a guide RNA, a complex formed by the Cas12i polypeptide or fusion polypeptide with the guide RNA, a nucleic acid, a vector, a vector system, a delivery system, a kit, a composition, and a method for modifying a nucleic acid using the components described above.


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