The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 21, 2025
Filed:
Mar. 26, 2019
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Dongeun Huh, Villanova, PA (US);
Andrei Georgescu, Philadelphia, PA (US);
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Abstract
Systems and methods for multilane vasculature and multiorgan vascular-vessel fluidic interfaces in in vitro models. The method includes embedding at least one tissue into a 3D structure, forming a vascular interface for nutrient perfusion into the tissue or tissues, tuning the vascular interface or interfaces together or separately to possess a property of a native biological target tissue or target environment by modifying a vessel attribute; and lining a fluidic interface channel, for providing a growth fluid in a physiologically recapitulating manner. The 3D structure includes a vasculogenic element for angiogenesis or vasculogenesis.