The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2025

Filed:

Apr. 15, 2019
Applicants:

Nof Corporation, Tokyo, JP;

Universita' Degli Studi Di Padova, Padua, IT;

Inventors:

Hiroki Yoshioka, Kawasaki, JP;

Midori Hirai, Kawasaki, JP;

Masaki Kamiya, Kawasaki, JP;

Gianfranco Pasut, Padua, IT;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/765 (2006.01); A61K 31/785 (2006.01); A61K 38/27 (2006.01); A61K 47/54 (2017.01); A61K 47/56 (2017.01); A61K 47/59 (2017.01); C08G 81/00 (2006.01); C08G 81/02 (2006.01);
U.S. Cl.
CPC ...
C08G 81/028 (2013.01); A61K 38/27 (2013.01); A61K 47/54 (2017.08); A61K 47/595 (2017.08);
Abstract

The invention provides a modified bio-related substance that shows further prolonged half-life in blood and further improved stability in the blood of living organisms. In particular, the invention provides a conjugate of a block polymer and a bio-related substance, which conjugate is represented by the following formula (I), wherein each symbol is as described herein.


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