The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 21, 2025
Filed:
Jun. 15, 2020
Applicant:
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Inventors:
Wayne A. Marasco, Wellesley, MA (US);
Elizabeth Baez, Ashburn, VA (US);
Matthew Chang, Brookline, MA (US);
Assignee:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/30 (2006.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/42 (2025.01); A61P 35/00 (2006.01); C07K 14/725 (2006.01);
U.S. Cl.
CPC ...
C07K 16/3092 (2013.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/4257 (2025.01); A61P 35/00 (2018.01); C07K 14/7051 (2013.01); A61K 2239/13 (2023.05); C07K 2317/21 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2319/03 (2013.01);
Abstract
MUC1 is overexpressed in many cancers, including those of the lung, colon, breast, ovary, and pancreas. Aspects of the invention are directed towards the discovery of monoclonal antibodies and fragments thereof, such as a human single chain variable fragment (scFv), that recognizes human MUC1-SEA.