The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2025

Filed:

Apr. 25, 2019
Applicant:

Children's Medical Center Corporation, Boston, MA (US);

Inventor:

Markus H. Frank, Cambridge, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 9/117 (2006.01); A61K 31/6615 (2006.01); C07K 14/47 (2006.01); C07K 16/30 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C07K 16/3053 (2013.01); A61K 31/6615 (2013.01); C07F 9/117 (2013.01); C07K 14/4702 (2013.01); G01N 33/5041 (2013.01); C07K 2317/21 (2013.01); C07K 2317/76 (2013.01);
Abstract

The present invention is directed to methods and compositions for modulating ABCB5+ stem cell activity. The invention also relates to assays and reagents for manipulating and characterizing compounds that modulate ABCB5+ cell signaling.


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