The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 21, 2025
Filed:
Oct. 30, 2020
Applicant:
Kookmin University Industry Academy Cooperation Foundation, Seoul, KR;
Inventors:
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); A61K 39/00 (2006.01); A61P 35/00 (2006.01); C12N 15/63 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 39/00 (2013.01); A61P 35/00 (2018.01); C12N 15/63 (2013.01); C07K 2317/565 (2013.01); C07K 2317/92 (2013.01);
Abstract
The present disclosure relates to an antibody or an antigen-binding fragment thereof specifically binding to GRP94, and uses thereof. A GRP94 antibody or antigen-binding fragment thereof according to the present disclosure has very high specificity and affinity to GRP94, and excellent growth-inhibiting, infiltration-inhibiting, and angiogenesis-inhibiting effects on colorectal cancer cell lines, and thus can be useful as a composition for treating cancer, inhibiting cancer metastasis, and inhibiting angiogenesis.