The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 21, 2025
Filed:
May. 17, 2019
St. Jude Children's Research Hospital, Inc., Memphis, TN (US);
Baylor College of Medicine, Houston, TX (US);
Stephen Gottschalk, Memphis, TN (US);
Brooke Prinzing, Memphis, TN (US);
Giedre Krenciute, Memphis, TN (US);
ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC., Memphis, TN (US);
BAYLOR COLLEGE OF MEDICINE, Houston, TX (US);
Abstract
The application relates to a chimeric antigen receptor that targets Eph receptors and allows activation of co-stimulatory pathways. The application also relates to polynucleotides that encode the chimeric antigen receptor, vectors, and host cells comprising the chimeric antigen receptor. The application also relates to methods for preparing host cells comprising a chimeric antigen receptor in order to improve the in vivo effector function of the chimeric antigen receptor host cells.