The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 21, 2025
Filed:
May. 13, 2019
Applicant:
Phytovent Biopharma, Shenzhen, CN;
Assignee:
Phytovent Biopharma, Shenzhen, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07J 71/00 (2006.01); A61K 31/58 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07J 71/0005 (2013.01); A61K 31/58 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01);
Abstract
A derivative of sarsasapogenin is provided having a structure of formula I, A pharmaceutical composition of the aforementioned derivative of sarsasapogenin and use thereof are also provided. By systematic modification and derivatization of sarsasapogenin structure in combination with inhibitory activity assays on tumor cells, many derivative compounds are provided that have excellent inhibitory activity on tumor cells, particularly high inhibitory activity on the growth of various brain tumor cells, having potential wide application and tremendous value in treating various cancers.