The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2025

Filed:

May. 22, 2020
Applicants:

Ohio State Innovation Foundation, Columbus, OH (US);

University of North Carolina AT Greensboro, Greensboro, NC (US);

The Board of Trustees of the University of Illinois, Chicago, IL (US);

Mycosynthetix, Inc., Hillsborough, NC (US);

Inventors:

James Robert Fuchs, Columbus, OH (US);

Andrew Huntsman, Fort Jennings, OH (US);

Nicholas Hunter Oberlies, Greensboro, NC (US);

Chiraz Soumia Amrine, Greensboro, NC (US);

Huzefa Raja, Greensboro, NC (US);

Joanna Burdette, Chicago, IL (US);

Cedric Pearce, Chapel Hill, NC (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 513/22 (2006.01); A61K 31/542 (2006.01); A61P 35/00 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01);
Abstract

Disclosed herein are compounds, compositions, and methods for inhibiting a histone methyltransferase. The compounds are verticillin derivatives that exhibit anti-proliferative activity against cancer cells. The compounds, compositions, and methods can be used to treat a subject with cancer.


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