The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 21, 2025
Filed:
May. 09, 2024
Acerta Pharma B.v., Oss, NL;
Paul Allen Bethel, Cambridge, GB;
Lai Chun Chan, Cambridge, GB;
Katie Grace Cooper, Cambridge, GB;
Robert John Cox, Cambridge, GB;
Michael David Golden, Cambridge, GB;
Shaun Alan Hughes, Cambridge, GB;
Lucinda Victoria Jackson, Cambridge, GB;
Kirsty Jane Millard, Cambridge, GB;
Andrew John Phillips, Cambridge, GB;
Alexander James Telford, Cambridge, GB;
Jerry Evarts, Seattle, WA (US);
Michael Joseph Lawler, Waunakee, WI (US);
Remy E. J. N. Litjens, Weert, NL;
Peter Johannes Servaas Savio Van Eijk, Weert, NL;
Mathilda Maria Henrica Verstappen, Weert, NL;
Frank L. M. Vos, Weert, NL;
Eric Jurriën Zijp, Weert, NL;
Qiu Junying, Tianjin, CN;
Rustam Ferdinand Garrey, Salem, OR (US);
David Allen Short, Springfield, OR (US);
Angang Wang, Dalian, CN;
Acerta Pharma B.V., Oss, NL;
Abstract
The present disclosure relates, in general, to improved processes for the preparation of 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)-benzamide, particularly large-scale processes for manufacturing 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)benzamide and intermediates used in such processes.