The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2025

Filed:

Nov. 02, 2023
Applicant:

Astrazeneca Ab, Sodertalje, SE;

Inventors:

Ina Terstiege, Sodertalje, SE;

Stefan Schiesser, Sodertalje, SE;

Yafeng Xue, Sodertalje, SE;

Hui-Fang Chang, Sodertalje, SE;

Anna Ingrid Kristina Berggren, Sodertalje, SE;

Assignee:

AstraZeneca AB, Sodertalje, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/416 (2006.01); A61P 11/06 (2006.01); A61P 37/06 (2006.01); C07D 231/56 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61P 11/06 (2018.01); A61P 37/06 (2018.01);
Abstract

The present application relates to chemical compounds of Formula (A), and pharmaceutically acceptable salts thereof, that inhibit IRAK4 and can be used to treat respiratory diseases, cancer, inflammatory diseases, and/or autoinflammatory/autoimmune diseases. Formula (A): Rand Rare herein defined throughout the disclosure.


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