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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12448372 B1

PDFFull Text
Date of Patent:
Oct. 21, 2025

Filed:

Jul. 16, 2020

Class of triaromatic compounds targeting bifunctional phosphorylation site of stat3 and applications thereof

Applicant:

Shanghai Yuyao Biotech Ltd., Shanghai, CN;

Inventors:

Yihua Chen, Shanghai, CN;

Wenbo Zhou, Shanghai, CN;

Huang Chen, Shanghai, CN;

Zhengfang Yi, Shanghai, CN;

Xiufeng Pang, Shanghai, CN;

Mingyao Liu, Shanghai, CN;

Assignee:

SHANGHAI YUYAO BIOTECH LTD., Shanghai, CN;

Attorneys:

NKL Law

Bin Lu

Allen Xue

Primary Examiner:

Clinton A Brooks

Assistant Examiner:

Kendall Nicole Heitmeier

Int. Cl.
CPC ...
A61P 1/04 (2006.01); A61K 31/497 (2006.01); A61K 45/06 (2006.01); A61P 11/00 (2006.01); A61P 13/12 (2006.01); A61P 17/06 (2006.01); A61P 19/02 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61P 37/02 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01);
Abstract

Disclosed is a class of triaromatic compounds targeting a bifunctional phosphorylation site of STAT3, such as compounds represented by formulas (I) to (V), or pharmaceutically acceptable salts, hydrates, solvates, metabolites or prodrugs thereof. Further proposed are pharmaceutical compositions comprising the compounds represented by formulas (I) to (V). Further proposed are applications of the triaromatic compounds in the preparation of drugs for preventing and/or treating diseases caused or regulated by activation of the bifunctional phosphorylation site of STAT3.

Find Patent Forward Citations

Chen, Yihua. (2025). Class of triaromatic compounds targeting bifunctional phosphorylation site of stat3 and applications thereof (U.S. Patent No. 12448372). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12448372

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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