The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 21, 2025
Filed:
Nov. 10, 2023
Applicant:
Pfizer Inc., New York, NY (US);
Inventors:
Yuhang Liu, South Glastonbury, CT (US);
Ye Che, Niantic, CT (US);
Xiaoyuan Sherry Chi, Tenafly, NJ (US);
Philip Ralph Dormitzer, Sherborn, MA (US);
Jennifer Anne Nicki, Gales Ferry, CT (US);
Xiaojie Yao, East Lyme, CT (US);
Assignee:
Pfizer Inc., New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/245 (2006.01); C07K 14/045 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/245 (2013.01); C07K 14/045 (2013.01); C12N 7/00 (2013.01); C12N 2710/16134 (2013.01);
Abstract
Polypeptides and cytomegalovirus (CMV) antigens that include at least two introduced amino acid mutations relative to the amino acid sequence of the wild-type HCMV glycoprotein B (gB). For example, polypeptides stabilized in a conformation alternative to the gB postfusion conformation. Compositions including the polypeptides and uses thereof.