The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 21, 2025
Filed:
Aug. 28, 2019
Applicant:
Prokidney, Grand Cayman, KY;
Inventors:
Timothy A. Bertram, George Town, KY;
Deepak Jain, Winston-Salem, NC (US);
Assignee:
PROKIDNEY, Grand Cayman, KY;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/22 (2015.01); C12N 5/071 (2010.01); G01N 33/50 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
A61K 35/22 (2013.01); C12N 5/0687 (2013.01); G01N 33/5076 (2013.01); G01N 33/6803 (2013.01); C12N 2501/11 (2013.01); C12N 2501/12 (2013.01); C12N 2502/256 (2013.01);
Abstract
Provided herein are, inter alia, extracellular products (e.g., vesicles such as microvesicles, e.g., exosomes) produced by renal cells (such as bioactive renal cells, e.g., selected renal cells). Methods of altering components (such as miRNAs or proteins) of vesicles produced by cells, as well as methods of producing vesicles comprising various compounds are also included. Also provided are diagnostic and treatment methods.