The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2025

Filed:

Dec. 24, 2020
Applicant:

Eisai R&d Management Co., Ltd., Tokyo, JP;

Inventors:

Seiji Takemoto, Nagoya, JP;

Shuntaro Arase, Mizuho, JP;

Yuta Suzuki, Tsukuba, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); A61K 9/107 (2006.01); A61K 9/1272 (2025.01); A61K 31/713 (2006.01); A61P 13/02 (2006.01);
U.S. Cl.
CPC ...
A61K 31/713 (2013.01); A61K 9/107 (2013.01); A61K 9/1272 (2013.01); A61P 13/02 (2018.01);
Abstract

Disclosed is a pharmaceutical composition comprising a lipid complex, wherein the lipid complex comprises a double-stranded ribonucleic acid comprising a sense strand consisting of a nucleotide sequence set forth in SEQ ID NO: 145 and an antisense strand consisting of a nucleotide sequence set forth in SEQ ID NO: 146, and a pH of a solution of the lipid complex is 5.0 or less, or 7.5 or more.


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