The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2025

Filed:

Jul. 06, 2020
Applicants:

Zhejiang Hisun Pharmaceutical Co., Ltd., Zhejiang, CN;

Shanghai Aryl Pharmtech Co., Ltd., Shanghai, CN;

Inventors:

Hejun Lv, Shanghai, CN;

Yutao Ma, Shanghai, CN;

Haibo Qiu, Shanghai, CN;

Wenwen Zhao, Shanghai, CN;

Taishan Hu, Shanghai, CN;

Lei Chen, Zhejiang, CN;

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 45/06 (2006.01); A61P 9/00 (2006.01); A61P 11/00 (2006.01); A61P 11/06 (2006.01); A61P 29/00 (2006.01); A61P 35/02 (2006.01); A61P 37/00 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 45/06 (2013.01); A61P 9/00 (2018.01); A61P 11/00 (2018.01); A61P 11/06 (2018.01); A61P 29/00 (2018.01); A61P 35/02 (2018.01); A61P 37/00 (2018.01); C07D 487/04 (2013.01);
Abstract

The present invention relates to an alkyne derivative, a preparation method for same, and applications thereof in medicine. Specifically, the present invention relates to the alkyne derivative as represented by formula (I), the preparation method for same, a pharmaceutically acceptable salt thereof, and uses of them as a therapeutic agent, specifically as a phosphoinositide 3-kinase γ (PI3Kγ) inhibitor, where the definitions of the substituents in formula (I) are identical to the definitions in the description.


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