The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 21, 2025
Filed:
Jun. 29, 2022
Applicant:
The Regents of the University of Colorado, Denver, CO (US);
Inventors:
Ding Xue, Louisville, CO (US);
Yu Peng, Bejing, CN;
Man Zhang, Beijing, CN;
Lingjun Zheng, Boulder, CO (US);
Qian Liang, Beijing, CN;
Hanzeng Li, Louisville, CO (US);
Jau-Song Yu, Taoyuan, TW;
Jeng-Ting Chen, Taoyuan, TW;
Assignee:
The Regents of the University of Colorado, Denver, CO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/353 (2006.01); A61K 31/336 (2006.01); A61K 31/4025 (2006.01); A61K 31/7048 (2006.01);
U.S. Cl.
CPC ...
A61K 31/353 (2013.01); A61K 31/336 (2013.01); A61K 31/4025 (2013.01); A61K 31/7048 (2013.01);
Abstract
The invention provides novel compositions and methods for the treatment of Radiation-Induced Bystander Effects (RIBE), resulting from radiation exposure. In one preferred embodiment the inventions includes novel therapeutic agents, including but not limited to quercetin and quercetin analogs, as well as E64, CA074, CA074Me, that interfere with the activity of Cathepsin B.