The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2025

Filed:

Dec. 20, 2021
Applicant:

Takeda Pharmaceutical Company Limited, Osaka, JP;

Inventors:

Daniel J. Sexton, Melrose, MA (US);

Ryan Faucette, Melrose, MA (US);

Jon A. Kenniston, Hingham, MA (US);

Gregory P. Conley, Arlington, MA (US);

Andrew Nixon, Hanover, MA (US);

Christopher Tenhoor, Hopkinton, MA (US);

Burt Adelman, Concord, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); A61K 39/00 (2006.01); C07K 16/36 (2006.01); C07K 16/40 (2006.01); C12Q 1/37 (2006.01); C12Q 1/56 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); C07K 16/36 (2013.01); C07K 16/40 (2013.01); C12Q 1/37 (2013.01); C12Q 1/56 (2013.01); A61K 2039/505 (2013.01); C07K 2317/76 (2013.01); C12Y 304/21034 (2013.01); C12Y 304/21038 (2013.01); G01N 2333/4713 (2013.01); G01N 2333/96455 (2013.01); G01N 2333/96458 (2013.01); G01N 2500/02 (2013.01); G01N 2500/20 (2013.01); G01N 2800/224 (2013.01); G01N 2800/50 (2013.01); G01N 2800/52 (2013.01);
Abstract

Methods and assays for determining the activation level of the plasma kallikrein (pKal) system and the uses thereof for assessing the activity of pKal modulators on the pKal system.


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