The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2025

Filed:

May. 12, 2023
Applicant:

Waters Technologies Corporation, Milford, MA (US);

Inventors:

Szabolcs Fekete, Ville la Grand, FR;

Matthew A. Lauber, North Smithfield, RI (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 30/56 (2006.01); B01D 15/16 (2006.01); B01D 15/38 (2006.01); G01N 30/52 (2006.01); G01N 30/02 (2006.01);
U.S. Cl.
CPC ...
G01N 30/52 (2013.01); B01D 15/166 (2013.01); B01D 15/3847 (2013.01); G01N 30/56 (2013.01); G01N 2030/027 (2013.01); G01N 2030/562 (2013.01);
Abstract

The present disclosure is directed to liquid chromatography columns and methods utilizing a stationary phase sorbent having two or more gradient factors. Each of the two or more gradient factors varies in a progressive manner along a length of the stationary phase sorbent in a direction from an inlet to an outlet of the column (i.e., along a length of the column). As a result of including these new continuous stationary phase gradients, new selectivities allowing for separation and analysis of complex samples including large biomolecules is achievable.


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