The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2025
Filed:
Dec. 12, 2019
Applicant:
Amgen Inc., Thousand Oaks, CA (US);
Inventors:
Serena Bisagni, Cambridge, GB;
Amin Bornadel, Cambridge, GB;
Beatriz Dominguez, Cambridge, GB;
Jacques Lepaih, Cambridge, GB;
Steven M. Mennen, Thousand Oaks, CA (US);
Ahir Pushpanath, Cambridge, GB;
Iustina Slabu, Cambridge, GB;
Jason Tedrow, Thousand Oaks, CA (US);
Simon J. Hedley, Thousand Oaks, CA (US);
Assignee:
Amgen Inc., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 17/12 (2006.01); C07D 213/73 (2006.01); C07D 295/205 (2006.01);
U.S. Cl.
CPC ...
C12P 17/12 (2013.01); C07D 213/73 (2013.01); C07D 295/205 (2013.01);
Abstract
A method for reducing a substrate selected from 2-methyl-5-nitropyridine and methyl 4-(2-fluoro-3-nitrobenzyl)piperazine-1-carboxylate is provided catalysed by a nitroreductase and a disproportionation agent.