The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2025

Filed:

Nov. 24, 2021
Applicant:

Carnegie Mellon University, Pittsburgh, PA (US);

Inventors:

Rachelle Simko, Pittsburgh, PA (US);

Adam Feinberg, Pittsburgh, PA (US);

Assignee:

Carnegie Mellon University, Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); A61L 27/16 (2006.01); A61L 27/18 (2006.01); A61L 27/36 (2006.01); A61L 27/38 (2006.01); A61L 27/50 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0062 (2013.01); A61L 27/16 (2013.01); A61L 27/18 (2013.01); A61L 27/3633 (2013.01); A61L 27/38 (2013.01); A61L 27/50 (2013.01); C12N 5/0012 (2013.01); C12N 5/0068 (2013.01); C12N 2531/00 (2013.01); C12N 2533/90 (2013.01); C12N 2535/00 (2013.01); C12N 2539/10 (2013.01);
Abstract

A method for micro-tissue encapsulation of cells includes coating a tissue scaffold stamp with an extracellular matrix compound; depositing the tissue scaffold stamp onto a thermoresponsive substrate; seeding the tissue scaffold stamp with a cell culture; incubating the cell culture on the tissue scaffold stamp at a temperature that is specified, wherein the cell culture forms a cell patch that is attached to the extracellular matrix compound; removing the thermoresponsive substrate by lowering the temperature; removing the tissue scaffold stamp from the cell patch to form a micro-tissue structure by dissolving the tissue scaffold stamp in a solvent; folding the micro-tissue structure by suspending the micro-tissue in the solvent to enable the cell patch to fold the micro-tissue structure; collecting the folded micro-tissue structure from the solvent; and administering the folded micro-tissue structure to an organism.


Find Patent Forward Citations

Loading…