The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2025
Filed:
Aug. 13, 2021
Applicants:
Biogen MA Inc., Cambridge, MA (US);
Samsung Bioepis, Yeonsu-gu, KR;
Inventors:
William C. Yang, Cary, NC (US);
Yao-Ming Huang, Cary, NC (US);
Marty Sinacore, Andover, MA (US);
Thomas Ryll, Weston, MA (US);
Jiuyi Lu, Ipswich, MA (US);
Jaesun Lee, Incheon, KR;
Kyngju Lee, Incheon, KR;
Hyoung Taek Lim, Incheon, KR;
Eunchong Yang, Seoul, KR;
Assignees:
Biogen MA Inc., Cambridge, MA (US);
Samsung Bioepis, Yeonsu-gu, KR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0018 (2013.01); C12P 21/00 (2013.01); C12N 2500/40 (2013.01); C12N 2500/60 (2013.01);
Abstract
The present invention pertains to methods of producing polypeptide of interest in cell cultures lacking glutamine. The present invention further pertains to a method of producing a protein of interest in a large scale cell culture, comprising supplementing the cell culture with nucleic acid synthesis precursors and/or corticosteroids.