The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2025
Filed:
May. 13, 2021
Ibio, Inc., Bryan, TX (US);
Matthew P. Greving, San Carlos, CA (US);
Phung Tu Gip, San Francisco, CA (US);
Mohan Srinivasan, Cupertino, CA (US);
Andrew Morin, San Mateo, CA (US);
Kevin Eduard Hauser, Jupiter, FL (US);
Jordan R. Willis, Hayward, CA (US);
Cody A. Moore, San Francisco, CA (US);
Christian Barrett, San Diego, CA (US);
Alex T. Taguchi, San Mateo, CA (US);
Angeles Estelles, Belmont, CA (US);
iBio, Inc., San Diego, CA (US);
Abstract
Provided herein engineered polypeptides that comprise a combination of spatially-associated topological constraints, wherein at least one constraint is derived from a CD25 reference target, and methods of selecting said engineered polypeptides. Further provided are methods of using the engineered polypeptides, including as positive and/or negative selection molecules in methods of screening a library of binding molecules such as antibodies. Further provided herein are CD25 antibodies selected using these engineered polypeptides.